Cisplatin 40mg m2 weekly cervical

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WebJul 23, 2024 · Cisplatin chemotherapy is acceptable Eastern Cooperative Oncology Group (ECOG) score 0-1 The expected survival was more than 6 months Women of childbearing age must have a pregnancy test (serum or urine) within 7 days before enrollment, and the result is negative, and they are willing to use appropriate contraceptive methods during … WebMar 1, 2024 · Chemoradiotherapy with weekly cisplatin at a dose of 40 mg/m 2 is widely used as a possible alternative, albeit without sufficient evidence. This clinical trial was conducted to prove the noninferiority of weekly cisplatin to 3-weekly cisplatin plus …

Cisplatin Every 3 Weeks Versus Weekly With Definitive ... - PubMed

WebCisplatin Vial. - Uses, Side Effects, and More. Cisplatin may cause severe kidney problems, nerve problems, and severe nausea and vomiting. Nerve problems may occur … dwi victim impact panel texas

353 Dose-dense NACT followed by CCRT in locally advanced cervical …

WebAug 28, 2024 · Hemoglobin ≥ 10.0 g/dl Leukocyte count ≥ 4000 cell/mm3 Adequate Renal Function defined as: Serum Creatinine ≤ 1.5 mg/dl within 14 days before admission to the study Patients with HIV infection (human immunodeficiency virus) must have a CD4 cell count ≥ 350 cells / mm3 measured within 14 days prior to study entry (no HIV test is … WebMar 1, 2024 · In the weekly arm, cisplatin was administered at 40 mg/m 2 once a week for seven cycles during the RT period. Criteria for dose reduction or delay were prespecified. … WebAug 1, 2024 · The sample size calculation of 47 patients provides 80% power to detect a difference in survival at the two-sided 5% significance level using the log-rank test; considering a 10% reduction, a total of 53 samples are required. This study is currently open, and 23 patients have been enrolled. dwivedi hotels palace on steps varanasi

Toxicity of concurrent chemoradiotherapy for locally advanced cervical ...

Head and Neck Cancer - Journal of Clinical Oncology

WebApr 10, 2024 · Cisplatin (40 mg/m2) was delivered weekly during external beam radiation therapy and once with brachytherapy. ... Extended-field irradiation and intracavitary brachytherapy combined with cisplatin chemotherapy for cervical cancer with positive para-aortic or high common iliac lymph nodes: results of arm 1 of RTOG 0116. Int J … WebNov 1, 2004 · Methods and materials: Locally advanced or high-risk early-stage cervical cancer patients treated with RT and concurrent weekly cisplatin at a dose of 40 … dwi virginia first offenseWebJan 4, 2024 · Cisplatin 40 mg/m 2 IV once weekly plus radiation therapy, 1.8-2 Gy daily per fraction, for six cycles or Cisplatin 50-75 mg/m 2 IV on day 1 plus 5-flurouracil (5 … crystal launcher how to install mods

"WebNov 23, 2024 · Patients will receive weekly cisplatin with their treatments at 40 mg/m2. Response rate, survival, and toxicity will be evaluated. Detailed Description: Toxicity will be assessed six times during this study. " - Cisplatin 40mg m2 weekly cervical

Cisplatin 40mg m2 weekly cervical

Concurrent weekly cisplatin and radiotherapy in routine

WebCisplatin3,a,bDay 1:Cisplatin 40mg/m2IV over 60 minutes. Repeat cycle weekly for 6 weeks with concurrent radiation. Other Recommended Regimens Cisplatin + … WebA multi-institutional observational study on the effects of three-dimensional radiotherapy and weekly 40-mg/m2 cisplatin on postoperative uterine cervical cancer patients with high …

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WebThe total dose of 50 Gy was given in 25 fractions within five weeks using standard fractionation. Concurrently with external radiotherapy, six cycles of chemotherapy were administered to all the patients as an intravenous infusion … WebAll patients had a type III radical hysterectomy and complete systematic bilateral pelvic lymphadenectomy. Post-operative adjuvant pelvic radiation therapy was given concurrently with weekly cisplatin 40 mg/m2 for 6 cycles to patients with at least one major risk or two intermediate-risk factors.

WebOct 1, 2024 · They received 6 cycles of weekly NACT with Carboplatin AUC 2 and Paclitaxel 80mg/mq, followed by CCRT (pelvic EBRT (45Gy) weekly Cisplatin 40mg/mq followed by cervico-vaginal BT-HDR... WebA multi-institutional observational study on the effects of three-dimensional radiotherapy and weekly 40-mg/m2 cisplatin on postoperative uterine cervical cancer patients with high-risk prognostic factors

WebFeb 10, 2024 · Day 1: Docetaxel 60-75mg/m 2 IV over 60 minutes, followed by: Day 1: Carboplatin AUC 5-6 IV over 30 minutes. Repeat cycle every 3 weeks for 6 cycles. Paclitaxel + Carboplatin 3,7-9. Day 1 ... WebApr 4, 2024 · Cisplatin 40mg/m 2 weekly for up to 7 weeks, concurrently with radiotherapy at a dose of 2.0 to 2.27Gy per fraction with 5 daily fractions per week for 6 to 7 weeks to a total dose of 66Gy or ...

WebCisplatin 40mg/m 2 IV weekly concurrent with radiotherapy. Cisplatin + 5-FU 25 Day 1: Cisplatin 100mg/m 2/day IV. Days 1–4: 5-FU 1,000mg/m2/day continuous IV infusion for 4 days.

WebAbstract Introduction: Combination of external beam radiotherapy (EBRT) and High Dose Rate (HDR) brachytherapy (BT) with concurrent chemotherapy (Cisplatin 40mg/m2/weekly) is the standard treatment of approach for the carcinoma of uterine cervix. dwi vip classWebIntroduction: Combination of external beam radiotherapy (EBRT) and High Dose Rate (HDR) brachytherapy (BT) with concurrent chemotherapy (Cisplatin 40mg/m2/weekly) is the standard treatment of ... dwi vip repeat offenderWebMethods: All patients were randomly assigned (half in each group)to receive weekly cisplatin at a dose of 40 mg/m2 compared to 20 mg/m2, concurrent with radiotherapy … dwivedi actressWebMay 1, 2024 · The mean initial dose of LDC was 40 mg/m2. After PS adjustment, HDC was not associated with improved OS over LDC (hazard ratio = 0.94, 95% confidence interval = 0.80 to 1.04). Adjusting for PS, HDC was associated with an increased risk of acute kidney injury, neutropenia, dehydration/electrolyte disturbance, and hearing loss. dwiwarna boarding schoolWebSeven patients also received one to five cycles of cisplatin [CDDP] 40 mg/m2 weekly. They developed late complications of grade II VO (n=2), grade III RVF (n=1), grade III RB (n=1), grade II RB (n=4), and grade III SP (n=1) secondary to the treatment with cisplatin or iridium-192. The SP developed 30 months after ISBT and was treated with surgery. crystal launcher hacksWebConclusion: Concomitant chemoradiation with cisplatin 40 mg/m2 weekly x 6 using HDR brachytherapy represents a promising treatment of cervical cancer with an acceptable toxicity. Publication types Clinical Trial Clinical Trial, Phase II MeSH terms Adenocarcinoma / drug therapy Adenocarcinoma / pathology Adenocarcinoma / radiotherapy dwi vip class texasWebMar 31, 2024 · Chemotherapy consisted of at least four cycles of cisplatin 40 mg/m2 and nab-paclitaxel with escalating doses (10, 20, 33, 50, 70 mg/m2). Radiotherapy consisted … dwiwarna construction