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Oxazaphosphorines中文

Web"oxazacyclobutane"中文翻译 氧氮环丁烷；氧氮呾 "oxatyl"中文翻译 羧基 "oxazaphosphorine"中文翻译 [网络] 恶唑磷 "oxatricyclo"中文翻译 n.氧杂三环辛烷 "oxazaphosphorines"中文翻译 [网络] 恶唑磷酸 "oxatriazoles"中文翻译 [化学 冶金] 恶三唑 WebJan 1, 1989 · The cancerotoxic selectivity of oxazaphosphorines was further increased when mesna was introduced as a regional uroprotector. Mesna eliminates the risk of therapy-limiting urotoxic side effects of oxazaphosphorines. With mesna protection, these cytostatics can be given in higher doses with increased safety, and their therapeutic …

Activation of oxazaphosphorines by cytochrome P450: …

WebJan 31, 2012 · Oxazaphosphorines. The two oxazaphosphorines, cyclophosphamide [CAS No. 6055-19-2] and ifosfamide [CAS No. 3778-73-2] (Figure ), are used as cytostatic agents, especially in the chemotherapy of malignant tumours, and also in the case of autoimmune diseases and rheumatic disorders.Both substances are alkylating agents and are known … WebMini-review Activation of oxazaphosphorines by cytochrome P450: Application to gene-directed enzyme prodrug therapy for cancer Partha Roy a,*, David J. Waxman b,* a Forest Research Institute, A Division of Forest Laboratories, Inc., Harborside Financial Center, Plaza V, Jersey City, NJ 07311, United States b Division of Cell and Molecular Biology, … roof framing requirements https://robsundfor.com

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WebMay 1, 2010 · Abstract. The oxazaphosphorines (cyclophosphamide, ifosfamide and trofosfamide) are widely used in clinical practice for their antitumor and immunomodulatory activities. However, their use is ... WebCyclophosphamide, isfosfamide, and trofosfamide are the oxazaphosphorines derivative prodrugs, used in the treatment of various cancers and autoimmune disorders. This class of drugs requires bioactivation by the CYP enzyme to exert their antitumor activity (Fujita, 2006).Many different isoforms of the CYP enzyme carry out the bioactivation of the … Web氧化磷酸化通路. 在正常生理条件下，氧化磷酸化（OXPHOS）以 ATP 形式产生 95% 以上的细胞能量。. 该过程涉及五种不同的蛋白质复合体，即复合体 1-5。. OXPHOS 直接涉及合 … roof framing options

Cyclophosphamide : substance active à effet thérapeutique - VIDAL

Category:Oxazaphosphorines: new therapeutic strategies for an old class ... - PubMed

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Oxazaphosphorines中文

Oxazaphosphorine C3H4NOP - PubChem

WebOxazaphosphorine. Oxazaphosphorine pro-drugs that are commonly used in the treatment of different cancers are metabolized by cytochromes P450 producing aldophosphamides … WebOxazaphosphorines are a class of bi-functional alkylating agents that have been extensively investigated in the past 50 years for their anticancer and immune-regulating activities,

Oxazaphosphorines中文

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WebThe oxazaphosphorines including cyclophosphamide (CPA), ifosfamide (IFO), and trofosfamide represent an important group of therapeutic agents due to their substantial antitumor and immuno-modulating activity. CPA is widely used as an anticancer drug, an immunosuppressant, and for the mobilization of hematopoetic progenitor cells from the … WebThe oxazaphosphorines including cyclophosphamide (CPA), ifosfamide (IFO), and trofosfamide represent an important group of therapeutic agents due to their substantial …

WebOxazaphosphorines are prodrugs that require an activation by cytochrome P450 (CYP). CPA is mainly metabolized (>80%) to phosphoramide mustard while only 10%-50% of IFO is transformed in the alkylating entity, isophosphoramide mustard and 50%-90% of IFO release chloroacetaldehyde, a nephrotoxic and neurotoxic metabolite. ... Web奥沙西泮（Oxazepam），別名去甲羟安定，商品名舒宁（Serax），是苯二氮卓类镇静催眠药，与同类药物相比半衰期较短，不经过肝脏代谢，与之类似的药物只有劳拉西泮，临床 …

WebApr 1, 2012 · As such, the therapeutic efficacy, off-target toxicity, and unintentional drug-drug interactions of oxazaphosphorines have been long-lasting clinical concerns and heightened focuses of scientific literatures. Recent evidence suggests that xenobiotic receptors may play important roles in regulating the metabolism and clearance of … Web"oxazacillin" 中文翻譯 ： 苯唑西林 "oxazepams" 中文翻譯 ： n. [藥] 去甲羥基安定；氯羥氧二氮草 "oxazaborolidines" 中文翻譯 ： [網絡] 雙環氮氧硼狀產物 "oxazepamum" 中文翻譯 …

Web开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 roof framing members named partsWeb"oxazacyclobutane" 中文翻譯: 氧氮環丁烷；氧氮呾 "oxazepams" 中文翻譯: n. [藥] 去甲羥基安定；氯羥氧二氮草 "oxazacort" 中文翻譯: 去氟可特,醋噁唑龍 "oxazepamum" 中文翻譯: 去 … roof framing purlinsWebBackground: Oxazaphosphorines (cyclophosphamide (CPA), ifosfamide (IFO)) are major alkylating agents of polychemotherapy protocols but limiting their toxicity and increasing … roof framing software programsWebThe oxazaphosphorines. The oxazaphosphorines. The oxazaphosphorines Cancer Treat Rev. 1983 Sep;10 Suppl A:3-15. doi: 10.1016/s0305-7372(83)80002-4. Author N Brock. PMID: 6627244 DOI: 10.1016/s0305-7372(83)80002-4 No … roof framing terminology constructionWeboxazaphosphorine ( plural oxazaphosphorines ) ( organic chemistry) Any saturated six-membered heterocycle containing three carbon atoms and one each of oxygen, nitrogen and phosphorus, especially one in which the phosphorus atom is linked to both the nitrogen and oxygen atoms. ( medicine) Any of a family of anticancer drugs that contain this ... roof framing spacingWebAspects of the disclosure are directed to a technique for sequential electroporation that provides for a delivery of multiple electrical pulses separated in time to cells, cell particles, lipid vesicles, liposomes, or to increase efficiency of entry of one or more agents of interest into cells, cell particles, lipid vesicles, liposomes, tissues, or derivatives thereof, and to … roof francehttp://www.ichacha.net/oxazaborolidines.html roof framing valley rafter